I use bullseye, 700x or titegroup if I want efficiency and I use longshot and power pistol if I want the most velocity. Those powders work in semi autos and revolvers, but if I want even more velocity for 38/357 or 44 mag in a rifle length barrel or even some semi auto rifle calibers like 300 aac blackout or 7.62x39 I'll use 2400 or lilgun powder. Unigue is also a powder I use, but it falls in between both of the fast and slower burning powders I mentioned. I've actually had some very good accuracy using 15 grains of unique behind some homemade powder coated 130 grain lead 30 cal bullets fired from a 308 win bolt action rifle. Using neck sized brass I was getting clover leaf groups at 100 yds.